[amatic]

> If these drugs cure trauma-derived addictive behaviors, that's just so extremely interesting, mechanistically.

So much this. I think going off semaglutide makes the weight come back, so it would seem that semaglutide doesn't change the circuits of trauma and addiction permanently, but it does something to them. The theory that obesity is a result of food addiction is pretty revolutionary, and now having alcoholism confirmed to respond to the same drug really supports the theory. Additionaly, if both are caused by childhood or development traumas, that opens other treatment options, and maybe some forms of change in how we as a society look at addictions. But maybe I'm going too far.

[vl]

Statistically going off makes some of the weight to come back on average. I.e. some people can keep the weight off when they are thin, and others need to take maintenance dose of semiglutide forever.

[nisegami]

I was forced off of dulaglutide after the supply ran out in my country and have put back on all the weight I lost, but slower than expected.