PDF to text tools can extract some text, but get confused by tables, maths, etc.
You can annotate a PDF with the raw actual text, which is then used by screen readers, but typst (and LaTeX currently) don't do this. It certainly isn't trivial to do, but it would be useful.
The other option would of course be to produce HTML, which (unless you do horrible things) is generally very accessible, but neither typst or LaTeX do this well (LaTeX does it OK, but I find I usually need to clean up the result).
You can annotate a PDF with the raw actual text, which is then used by screen readers, but typst (and LaTeX currently) don't do this. It certainly isn't trivial to do, but it would be useful.
The other option would of course be to produce HTML, which (unless you do horrible things) is generally very accessible, but neither typst or LaTeX do this well (LaTeX does it OK, but I find I usually need to clean up the result).