[nomadpenguin]

The catch with deep brain stimulation currently is that it's only SOTA for implanted electrodes, meaning it's incredibly expensive, and while DBS implantation is very safe for a brain surgery, it's still a brain surgery. tTIS is very investigational and neuromodulatory focused ultrasound is still quite a bit away from clinical applications. (Ablative focused ultrasound is FDA approved, but that's only for very specific indications.) There's also the Brainsway H series TMS coils that claim to stimulate deep structures, but the activation of large amounts of cortical tissue makes the claim a little hard to verify.