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by jcul
942 days ago
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In Ireland, I'm sure I've seen 325mg doses of aspirin and been puzzled by it. I assumed it was just a little bit stronger than paracetamol. While that's probably true, I can see now it's a bit arbitrary too. Though maybe I'm misremembering or thinking of aspirin someone brought from the US. When I look up one of the most common asiprin brands here, it seems it is 300mg, not 325. https://phelans.ie/products/dispirin-direct-tablets-24s |
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325mg is 5 "grains".
"A grain is a unit of measurement of mass, and in the troy weight, avoirdupois, and apothecaries' systems, equal to exactly 64.79891 milligrams"
https://en.wikipedia.org/wiki/Grain_(unit)
81mg = 1.25 grains.
What ends up happening is a big study is done on an existing formulation of an old drug, results look good, and then you have to ask yourself: do you mess around with the dosing to get a round number, or go with what's been proven?