Yes: they use, for lack of a better term, DJB cryptography, and like many modern cryptosystems they eschew negotiation, so it's not straightforward to fit NIST algorithms in.
it's entirely straight-forward to substitute AES-256-GCM for ChaCha20/Poly1305 in Wireguard, and the result, while not "wireguard" is substantially faster than Wireguard.