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by fredgrott 934 days ago
For context, as WSJ gets things wrong...there are 3 feedback loops to noradrenaline and its the over increase of noradrenaline that cause anxiety disorders:

1. GABA 2. Serotonin 3. CBD

CBD is not just THC which is somewhat not effective but other amines such as one in chocolate that gives you the runner high.

My bias is that 50% of ADHD'ers have anxiety disorders due to noradrenaline running high..in my case I take GABA, L-theanine and chocolate to control it.

2 comments

> My bias is that 50% of ADHD'ers have anxiety disorders due to noradrenaline running high.

I think this is partially the case. I think the glutamatergic system is messed up which causes the release of too much norephenephrine and dopamine.

After a while this causes down-regulation and the actual neuron pathways develop "bad connection" e.g. the frontal lobe develops bad habits/poor motivation.

At this point you're stimulated via norephephine but you have poor motivation/focus because of the dopamine tolerance.

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NAC is an interesting candidate you might find interesting as it directly effects the glutamatergic system. I was recommended this by my doctor and had a good personal experience (I'm not a doctor, etc).

NAC has been a game changer for me, especially with BFRBs.
I'm curious what is it about chocolate that helps the anxiety. I only know it to be a stimulant, or its extracts to increase brain bloodflow).
I'm curious too. I know cocoa contains a lot of Theobromine which is very similar to caffeine (caffeine is Methyl-theobromine) although it does behave a little different. Cocoa also has a little caffeine as well.

I would think these two would make anxiety worse?

GABA and L-theanine make a lot of sense as these will directly impact the glutamatergic system and are well known to improve anxiety (and are also synergistic with stimulants especially caffeine).