[ofou]

My rationale comes back to the fact that biomolecule's function is dictated by its structure, so, it seems critical to have spatiality of some sort to achieve qualities of living systems.

[groestl]

You might mean that with "time", but I think recursiveness with a delay is the critical part (and to some extend, is achieved with spatiality).

[ofou]

I mean 3D aware parameters.