Hacker News new | ask | show | jobs
by derefr 938 days ago
You don't just sterilize fabric with bleach. (How would that even work? Hang the gown, spray the bleach on it, and let it drip off?) You sterilize fabrics with bleach + water + detergent + heat + agitation — with the goal not being to lyse the spores/other germs, but rather to detach all the contaminants from the fabric and suspend them in the water — which then gets flushed away.

In theory, bleach could help decrease the adhesion of the spore to a surface. A possible mechanism would be if it oxidized — and so weakened/destroyed — some spiky organic hooks that the spores were using to adhere to the fabric.

Of course, agents other than bleach — things not normally considered biocides, in fact — would likely be a lot more effective at removing spores during fabric washing, since the goal is detachment, not lysing the spore.

The obvious things (detergents themselves, and other soaps) would work, of course, to varying degrees.

But also, less-obvious things could provide benefits here. For example, if spores tended to stay adhered to fabrics because they possessed a rough proteinous exosporium that acted sort of like nano-scale velcro, then conditioners (yes, like the kind you use in hair) might get that protein coat to relax and lay flatter, in a way that disrupts the velcro-like effect.

Lubricants might also work, by "filling up" the rough valleys of the spore's surface. (Of course, you'd then need an extra wash cycle to remove the lubricants.)

3 comments

There are some really amazing detergents out there. My go-to for cleaning anything I don't have specific information about is Tergajet. It's gentle, extremely powerful, low-foaming (so machine compatible), oxidizing, bleach compatible, and contains a protein degradation enzyme potent enough to disrupt prions: https://technotes.alconox.com/detergents/tergazyme/do-enzyme...

The downside to this magic stuff is that it's fairly expensive ($45 for 4 pounds). So, not for wanton use. But well worth it to solve tough problems or when time is more important than money.

oxidizing and bleach compatible is an unusual pairing is it not? There are a bunch of chemicals you can't mix with bleach because you create chemical weapon precursors if you do. Even the precursors can send you to the ER.
>oxidizing and bleach compatible is an unusual pairing is it not?

I don't think it is. Isn't bleach itself an oxidizing agent?

Additionally, if the spore didn't get detached in the washing process, it's veeeery unlikely to get detached when you're just walking around being a nurse.

It might activate within the fabric if the conditions are right, but that's not very fast and you shouldn't be wearing scrubs contaminated by a nutritional substance for too long anyway.

Indeed; this is why washing hands with soap is effective even though the soap doesn't kill the pathogens.
The drying is probably the more effective part for mechanical disruption.

Similarly why bleach wipes > soaking in bleach for disinfecting surfaces, as alluded to in this paper.