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by LeeroyWasHere 948 days ago
Same, it would of been helpful if they cited certain types of products that have such high dosage that could cause such overdose and under which circumstances and on what scale was this an issue.

I was under the impression the absorption rate was so low, that it would take a massive oral ingestion to be concerning?

1 comments

Oh well, so it seems to be a very specific case.

>Cases of vitamin D overdose have recently been reported in young children following the use of food supplements fortified with this vitamin. These cases present as hypercalcaemia (excessive calcium in the blood), which can have serious consequences on the kidneys such as lithiasis or nephrocalcinosis (calcium deposition in the kidneys).

https://www.anses.fr/en/content/vitamin-d-children-use-medic...

I can tell you that I was diagnosed with low vitamin D, and was prescribed high doses to bring up my levels.

This resulted in multiple bouts of kidney stones, which I can wholeheartedly not recommend.

I don't take vitamin D supplements anymore.

Vitamin K2 and Magnesium are required for proper utilization of vitamin D. If they are not present, Calcium can build up in the bloodstream causing multiple possible issues. Were these prescribed along with it? If not, the doctor trying to naively solve a problem without any actual critical thinking. Which is understandable given the breadth of things they have to deal with, but unfortunate. Boron may be another significant required co-factor, but I’m not read up on that one.

Basically all vitamins and minerals have very complex interactions, and if you start taking megadoses of one, then it can surprising effects like:

* Cause accelerated utilization of a co-vitamin, causing low levels in these, and rendering the megadoses vitamin ineffective.

* Block or bypass the pathways that utilize a vitamin, causing to high a levels of another vitamin.

* Rendering measurably normal levels of a vitamin ineffective, through competition or exhaustion of the resources the secondary vitamin relies on.

B vitamins for example have complex interactions with each other. I cannot offhand remember the specifics, but if I recall correctly things like “energy” drinks stuffed with megadoses of a vitamin can result in the symptoms of deficiency of another B vitamin despite having normal levels.

Prescribing Vit D without Vit K2 (and possibly) Magnesium is simply malpractice. I take Vit D myself and after a few minutes of googling it is abundantly clear that it should not be taken in isolation.