[glitchc]

Certainly, if there's medical research indicating that melatonin is safe, all the better. As long as we're following the scientific process to generate a reproducible body of knowledge supporting the assertion that melatonin is safe.

[fnordpiglet]

Yeah. My point was though beyond random controlled trials we actually understand melatonin at a really fundamental level, and it’s not just that we understand it, but we identified it in as far as I can tell all vertebrates. That’s stronger than RCT’s. It’s like questioning we know whether blood infusions are actually effective at treating blood loss.