[epistasis]

The hypothesis was under great duress even in 2004, when I took a protein structure course that spent a lot of time on prions and the beta amyloid. Many people have devoted their careers to chasing this down, only one as far as we know published impactful fake data.

However, the particular faked data, despite lots of citations, has apparently not lead to any clinical trials:

> Did the AB*56 Work Lead to Clinical Trials? That’s a question that many have been asking since this scandal broke a few days ago. And the answer is that no, I have been unable to find a clinical trial that specifically targeted the AB*56 oligomer itself (I’ll be glad to be corrected on this point, though).