[Obscurity4340]

To what extent do you think this addresses root causes? Like, does it physiologically compel them to be less hungry or what?

[petesergeant]

Yes, that’s exactly what it does. My hunger is absolutely diminished, and my reward feedback from eating are also diminished.

[Obscurity4340]

Is developing tolerance/dose escalation a prescient issue here?

[petesergeant]

People move through the different doses at different speeds, and most people seem to find a stopping, long-term dose, but also there are people complaining that they’ve hit 15 and it’s starting to wear off. There’s also not a well-developed stopping protocol, other than “this is a drug for life but maybe start spreading out dosage”.