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by gilleain
959 days ago
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Nice. A few points: * This protein acts as a PETase - see also <https://news.ycombinator.com/item?id=37659327> - but may work at room temperature, and more efficiently * The term 'artificial protein' is a bit awkward - it's a modified version of an existing protein from an anemone (see : <https://www.rcsb.org/structure/4tsy>) * The scaffold protein is a pore-forming structure - where multiple trans-membrane helices come together, like melittin in bee venom - so they claim it could work as part of a membrane-bound complex |
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I agree. The proper term would be engineered protein, since it is a fusion of two existing protein domains: an already engineered cutinase (a PETase ancestor) with a pore-forming protein (FraC).