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by astrange 967 days ago
> - Anti-histamine (cetirizine hydrochloride aka Zyrtec) as needed - I'm allergic to my wife's dog and some nights I feel like I have bugs crawling on my skin. It can even wake me up.

Antihistamines are associated with increased dementia if you take the wrong ones, so it's not a good way to get more sleep. Melatonin, trazodone or a newer sleep drug is safer.

1 comments

that seems to be associated with benadryl:

https://www.health.harvard.edu/blog/common-anticholinergic-d...

which is sometimes used for it's drowsy effect. cetirizine/loratidine are non-drowsy and I don't see any association known with dementia

Yeah, Benadryl is a weird drug. Look at its interactions with various receptor sites in humans: https://en.wikipedia.org/wiki/Diphenhydramine#Pharmacology
Benadryl does nothing to me except kill my deep and REM sleep and leave me "sleeping" but conscious. I'm exhausted the next day. I only take cetrizine.
agreed, any drowsy things seem to turn off weird parts of my brain but im left feeling like an awake zombie