| As a general rule of thumb, diseases varients that evolved within mammal type X proliferate the most within mammal type X populations - the varient can jump to mammal type Y but tends to be a relatively rarer occurrence and tends to go with a bit of further evolutionary variation. FIV is not the same as HIV (Feline, Human, but they're similiar) and so to with prion diseases. Mad Cow disease came about from feeding large quantities of ground up cow offal from abattoirs mixed up with grains to make 'tasty' feed pellets .. eventually a cow prion disease 'perfected' itself and went on to occassionally(?) affect humans - more common in cows than humans, etc. With human cannabilism, we know about Kuru from the Fore people in PNG who, like many other groups in the highlands, practiced cannabilism as a mortuary ritual, a funeral practice to retain the essence of someone respected. Kuru was a specific human to human variation that evolved to become more common and overcome the defences against human -> human prion defence I mentioned earlier. We have other reasons to suspect cannibalism was common elsewhere .. such as the documented European practice of medicinal cannibalism and the fashion of consumming bitumised mummies. https://www.smithsonianmag.com/history/the-gruesome-history-... https://www.mentalfloss.com/posts/eating-mummies-as-medicine But, ahh, yeah - these days genetics is the thing, markers for defences against human prion diseases are a thing talked about in a group of papers post Kuru. |