The main problem that I have with extensions is:
"It can:
Read and change all your data on all websites"
Having my own, local extension I don't have to actually think whether I added some sensitive stuff to be exempt from permissions or not.
uBlock Origin is weak when it comes to new DOM elements dynamically created after the page has ostensibly loaded. Most of its powerful "cosmetic filter" selection operators don't work on such elements. I suspect that could make it of limited use on a feed object in which new elements appear, if you want to filter specific elements. (Aren't "infinite" feeds lazily loaded by JS?)
Still, much smarter to try it first to see if it fits your use case.