[hadley]

Quarto will support output to typst in the upcoming 1.4 release: https://quarto.org/docs/prerelease/1.4/typst.html

I think the big different between quarto and typst is the scope. quarto is a tool for combining prose and computation to generate many different output types (HTML, PDF (via latex), PDF (via typst), PPT, ...) through the power of markdown/pandoc. typst is a typesetting system for turning plain-text markup in to beautiful PDFs.

I think you're much more likely to want to write typst by hand than latex, but out of the box it doesn't provide any tooling for combining writing and computing (if that matters to you).