[wizofaus]

> any condition that doesn't impact survival until sexual maturity

Diseases that impact even just appearance can surely make you less attractive as a mate though. And larger goiters can impede breathing or swallowing. So I'd be suspicious of the idea that we've been significantly deficient in iodine for extended periods of our evolutionary history.

[civilitty]

Large goiters are rare and the vast majority are not outwardly visible nor do they impact breathing.

I’d be far more suspicious of applying modern standards of beauty to humans that lived hundreds of thousands of years ago.