[garrettgrimsley]

If you use uBlock Origin you can do

     www.linkedin.com##:matches-path(feed).scaffold-layout__main
     www.linkedin.com##.global-nav__primary-link.global-nav__primary-link--active.app-aware-link

The former will block the main content of the page while on the /feed/ path, while the latter will block the "Home" button in the header nav.

[jxramos]

wow I didn't know uBlock Origin was also capable of DOM cleanup. I really need to give that tool a second look.