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by lelanthran 975 days ago
> except our bodies already kinda do that on their own

> how would killing species of gut biota would helpful? helpful for whom to accomplish what??

OP wasn't talking about practical uses, he was talking about further experimentation in which the researchers narrow down exactly which gut bacteria has the effect.

Something like a binary search, or a git bisect.

2 comments

insert this.gif :-). One of the things that would be interesting would be to understand if a specific kind of bacteria in the gut was the cause or if it was a ratio of some sort. One could imagine an easy to use diagnostic test[1] that could help inform you if you needed to do something or not.

If this causality pans out (and it would if it was replicated several times) then this would go a long way to helping people figure out if they needed to do something to avoid "early onset Alzheimers" or even Alzheimers in general. An acquaintance had a fecal transplant (yeah it sounds yucky but it isn't really) which consisted of a course of broad spectrum anti-biotics followed by the introduction of a "non-Cdiff gut biome". It "cured" their issue completely and it hasn't returned.

[1] When the Microbiome project was a thing I submitted mine. The fecal test was pretty easy (if 'yucky' from a poopy sort of way).

> git bisect

please forgive me for reading this as 'gut bisect' the first time around :)