| Stanfield's logic is simply wrong. 1. Spermidine found to increase lifespan and fertility in mice. 2. Spermidine levels not found to increase in blood or certain tissues when fed to mice. 3. Therefore, 1 is wrong. Finding 2 in no way disproves 1. Facts which could be consistent with both 1 and 2 being true: - spermidine metabolites are responsible for benefits - while spermidine levels are maintained, excess spermidine is used beneficially - experimenters in 2 simply haven't looked in the right tissues And so on. TFA says there were observed phenotypic improvements (follicular health, oocyte number and quality), which categorically trump 2's failure to observe increase in spermidine levels. And none of this says anything directly about spermidine's effects in humans |