[fortran77]

This is caused from eating too much, not a decline in “metabolism”

[smileysteve]

So, the combination of the research and my anecdotes - and your response seems to be

That by our early 20s our metabolism has already slowed (sugary food, alcohol, precipitous drop in activity)

[fortran77]

No, our metabolism isn't "slow" (for 99% of people). People just start eating much more and moving much less.

[tristor]

Insulin resistance and PCOS absolutely have effects on metabolism. It’s very well studied.