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by tea-coffee
978 days ago
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I understand. I meant "bit different" in the nuanced context of this study. As the authors note in their introduction of the paper [1]: "Regrettably, these studies used ascorbic acid, a compound associated with the induction of metabolic acidosis and acidemia [15]. This makes it uncertain whether the unclear effects in human sepsis were due to the administration of a suboptimal preparation of the study medication. In contrast, sodium ascorbate (NaAscorbate) has a physiological pH, does not contribute to acidosis, can be given at a much greater dose, and may carry a different efficacy profile." 1 = https://ccforum.biomedcentral.com/articles/10.1186/s13054-02... |
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The body can react differently to salt vs pure form for the same active ingredient - eg crack vs cocaine