Although I've used the "Display" tab of the "System" pane of the Settings app in Windows 10 to change the scaling factor (labeled as "Scale and Layout"), I cannot make sense of your comment.
Every time I tried to scale windows UI in "software" way, as you just described it, I would encounter bug after bug after bug either in windows or apps or taskbar. After a realization that windows will never get UI scaling right, I decided to do "hardware" scaling, meaning, I still keep my windows scaling at 100%(recommended), but then I set the display resolution to a compatible lower one. My monitor is 38" and it's native resolution is 3840x1600. But when I set that resolution, there is no way in hell I would be able to read the fonts of the screen. So, instead, I set my resolution to 2560x1080, which doesn't look blurry, scales perfectly, and zero UI bugs.