[softg]

Worst case scenario the ad blocker can show a blank screen while pretending to play. Many people would prefer that to watching the ad imo.

[crtasm]

Like the ones for Spotify that would set your system volume to 1% when it detected an advert playing.

For video content an alternative would be to replace ads with a clip from the next video on your playlist/suggestions as a short "coming up next" preview.