[FabricPaul]

as per my other comment: "please correct me if I'm wrong, but I don't see anything about Cython handling multi-threading and I don't see anything about dynamic compilation on target. I just had a flick through their documentation, so if this stuff is in there then I missed it..."

[phtaylor]

When we designed Fabric, our goal was not to speed up Python, or JavaScript. Our goal was to build high performance multi-threaded applications on top or dynamic languages.

Fabric is for software developers who need to build high performance software, and also use dynamic languages.

V8 will continue to speed up, and may even get close to the speed of native code. But in that time, CPUs architectures will continue to gain more cores, widening the gap between multi-threaded code, and dynamic code.