Converting from vertical Enter to horizontal Enter when moving to the USA was a real frustration. I spent the first 4 years just importing British keyboards.
I came to the opposite conclusion and started importing US keyboards into the UK. I figured the UK layout I was used to wasn't different enough to justify existing, and the US layout has primacy because it's effectively the reference layout for programming language syntax design.
Yes and the missing key is frustrating too. Trying to find | and ` and \ on a laptop that doesn't have all the keys is so painful I just add the US keyboard layout to my menu bar.
I miss my chunky Enter key! Also whenever I have to write a currency value in £ I'm always annoyed that I need to go to the Wikipedia entry for "Pound sign" and copy it from there. There's probably an easier way, but it comes up so infrequently and I'm far too lazy to learn.