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by klevertree 992 days ago
Author here. As someone who works in pharma, organ on a chip models are not even close to being relevant to providing accurate PK curves for oral absorption. The state of the art is trying to make it work for cutaneous absorption and that's still not great/commercially useful.

My whole point is that there needs to be way more open data on pharmacokinetics. That's the only way we're going to solve this.