[AnthonBerg]

Hyperglycemia does too. (High blood sugar.) It’s known as diabetic rage. A number of things are happening there. Part of it is brain inflammation – experienced as suffering – and brain inflammation is directly behavior-modifying, causing aggression.

And indeed that’s what happens with traumatic brain injuries.

The same mechanism is behind the aggression sometimes displayed by cocaine users. Cocaine tamps down brain inflammation short-term, increases it long-term.

And indeed, people with traumatic brain injuries and central nervous system inflammation tend to have more problems with cocaine abuse.