[nszceta]

If you want to more or less permanently stop gum bleeding pre-brush with a dilute (50 to 200 ppm) solution of hypochlorous acid generated from vinegar acidified salt water (0.8-2%) with salt concentration (saline is 0.8-0.9%) then hit it with a $5 Aliexpress USB electrolyzer for about 30 seconds. The biofilms come right off, your toothbrush ceases to accumulate biological matter, and hypochlorous acid does not begin to show toxicity in keratinocytes until 10,000 ppm. It is extremely unpleasant in the mouth above 200 ppm so it is relatively easy to guesstimate.

[briHass]

Or just rinse (water pick even better) with a dilute bleach solution (0.25%). Make the solution fresh each time or every 24 hours, since sodium hypochlorite tends to decompose easily.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292655/

[nszceta]

Don't use bleach when you can easily make hypochlorous acid. Hypochlorous acid is bleach but acidified and much safer to the human body than bleach. Bleach is thousands of times more toxic to humans at the same HOCl concentration. You suggest using an OCl- concentration of 2500 ppm which would be extremely high for an equivalent therapeutic use of hypochlorous acid. You can easily use a 10 times lower concentration of hypochlorous acid for the same purpose, and it would still be total overkill. You can easily make hypochlorous acid with electrolysis safely or by mixing highly dilute bleach with highly dilute acid (vinegar) with a target pH range of 4-6. If your solution pH falls below about 4 there may be chlorine gas evolution which is generally undesirable. Above pH 4 it is not significant. Given the desired HOCl dilution hardly any chlorine gas will be emitted even if working in a confined space and using an excessively low pH. I recommend the electrolysis route for use in and around the body because the route is generally free from potentially harmful contaminants which may be in your bleach products. The bleach and acid method is useful to make a general purpose deodorant and disinfectant or if you trust your bleach to be free from harmful contaminants. https://www.dstec.com.my/wp-content/uploads/2020/04/pH-for-H...

Hypochlorous acid is hundreds of times more effective than bleach as a biocide because it is uncharged and can far more readily diffuse past the lipid bilayer of microbes to wreak havoc. Somehow, humans are generally much more immune to these effects. Whereas 0.1 ppm HOCl can kill most bacteria it takes approximately 10,000 ppm to damage most human cells. It is not recommended to use much over a handful of ppm in the nose and eyes.

[briHass]

Do you have any research papers supporting those assertions? At least with low-concentration bleach, it's been tested numerous times in RCTs without any harmful effects, besides bad taste. It's also proven effective, or at least as effective as prescription-based chlorhexidine mouthwash.

I'm interested in reading more, because I find diluting the bleach solution to be annoying and would obviously damage dyed fabrics if spilled.

[dsego]

Any thoughts on brushing with a concoction of peroxide and baking soda as recommended in this yt video?

https://www.youtube.com/watch?v=Cow6wNRJqoo

[nszceta]

Yeah, hydrogen peroxide is more toxic than hypochlorous acid.

[lost_tourist]

I just brush and floss once a day before heading off to bed and have none of these problems...