There are some annoying operational issues around it as well, common one: DNS hostnames for devices that only do SLAAC
If your network card breaks you switch it out, and you make sure your IPv4 settings apply to the new card.
If you fully rely on IPv6 you'll get a new address.
And if your devices self-update DNS then you have to make sure they pick the right address, as there can be many due to privacy extensions.
Lastly, combining privacy extensions plus hosting stuff is hard, as you don't know on which address a certain port is bound.
If your network card breaks you switch it out, and you make sure your IPv4 settings apply to the new card.
If you fully rely on IPv6 you'll get a new address.
And if your devices self-update DNS then you have to make sure they pick the right address, as there can be many due to privacy extensions.
Lastly, combining privacy extensions plus hosting stuff is hard, as you don't know on which address a certain port is bound.