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by pluijzer 1023 days ago
How susceptible to tolerance would the positive effect be? Would a long term smoker still have any benefit? Or is it like coffee, very quickly giving no benefit at all.
1 comments

This is a good question, along with what happens if that long term smoker then quits altogether.

If you had ways to moderate the withdrawal of things like caffeine and nicotine you could possibly try alternating regimes. Would probably do dreadful things to your heart though.