It's also very useful for simulation-based optimization. As an example, we use it extensively for the design of particle accelerators, where the simulations are typically expensive and need to run on supercomputers. We have built our own library[0] for enabling this, which in the end uses BoTorch (through Ax[1]) under the hood.
[0]: https://github.com/optimas-org/optimas [1]: https://ax.dev