Hacker News new | ask | show | jobs
by teuobk 1029 days ago
Except breast cancer screening, at least via mammography, doesn't save lives. See, for example: https://thennt.com/nnt/screening-mammography-for-reducing-de...
3 comments

I worked in a lab doing cancer detection via image AI (mammograms, mri, etc) back in 2008 or so, and even then we knew that mammography didn't save lives.
Read all of the caveats. None of this is still relevant. Cancer-specific mortality is definitely reduced.

There is no study powered enough to draw conclusions on all-cause mortality, which may not be the best measure anyway.

oh wow.

"This is an important, though uncommonly discussed, issue in the translation of evidence from cancer screening trials.1 It is known that overdiagnosis (treatment of cancers that would have been no threat), and high false positive rates (misdiagnosis) lead to medical harms and unnecessary surgeries, chemotherapy, and radiation...

...margin of benefit suggested by the analysis above it seems likely that if there is a benefit to screening mammography it is balanced out by mortal harms from overdiagnosis and false-positives"