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by acdha 1032 days ago
> Like pretty much anything involving malaria, I'd say this is a temporary victory at best. Malaria has a long history of developing drug resistance. And vaccine resistance could well prove similar.

We certainly shouldn’t give up on new research but I wouldn’t be so quick to reach the pessimistic conclusion. Vaccines are more robust than drugs and these cocktail approaches are good for requiring multiple favorable mutations to escape.

I do wish Intellectual Ventures had invested in the mosquito laser for more than a TED talk, though: there are plenty of bad things other than malaria and nothing evolves resistance to lasers.

1 comments

> We certainly shouldn’t give up on new research but I wouldn’t be so quick to...

My point was: We should continue with research as if this vaccine-drug combo had proven useless - because even if it is somehow perfect now, malaria might well evolve resistance to it faster than the Next Effective Thing can be discovered and brought to market.

I guess my thought was just to avoid giving the impression that this isn’t a big advance for millions of people even if it’s not perfect or permanent.