[einr]

If I can't pull my c64 with hardware available back in the day (or hardware one could realistically built back in the day) I'm not sure saying "runs on c64" is correct.

A 16MB REU could absolutely have been built in the 80s. It would have been absolutely astronomically expensive, but there’s no technical reason it could not be done. You seem to be confusing the SuperCPU with a plain REU expansion — the REU is just a bunch of RAM and an ASIC that talks to the 64 and allows it to store or retrieve banks of RAM (because obviously a 6502 cannot address more than 64K so instead you have to tell it to swap out system RAM) — there is no CPU on it.

The SuperCPU (65816) can indeed address up to 16MB directly and that is a different thing. The project in the OP runs on a stock C64 on the stock C64 CPU, it just needs a mountain of RAM that would have cost the equivalent of a house back then ;)