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by iten 1026 days ago
Small correction: BLAT is a local alignment tool Jim Kent also wrote. I think his assembler you're referring to is GigAssembler (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC311095/).
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I also love that all of their genomic tools are released as a virtualbox virtual machine and their entire site can basically be run locally with personal genomic data. I think it’s called genome in a box.

And if I remember correctly BLAT was so useful because it could be run on machines with less cpu power by loading more data into memory…or was it the other way around?