It's worth knowing that, according to some recent research, taking a topical antibiotic like this might have permanent impacts on microbiome in your nose (and lead to drug resistance.)
Yes, but systemic antibiotics are substantially worse in this regard as they change your entire systemic micro biome, and a chronic sinus infection is a permanent highly negative micro biome in your nose. Sometimes it’s better to hit the reset button than endure misery for the rest of your life :-)
Just to add this, my ENT prescribed a nasal probiotic prior to my surgery due to staph risk. I used it for 6 months prior to the surgery and now I continue to use it because, either it's a placebo or something special, it seems to improve the airflow in my nose beyond what I'd expect from just squirting some buffered water up my nose. Additionally, I seem to have fewer head-colds that also seem to resolve more rapidly (I have two small children, so my house is literally an incubator for infections). This is the product: https://liviaone.com/collections/probiotics/products/probiot... in case you were curious.