[Thews]

My bigger issue with the CGI model is the lack of handling connections as streaming. You can't parse a file while it's still being uploaded, and that can eat up a lot of memory on larger files.

I know startup times can take a toll like establishing db connections, cache checking (like redis), file imports, etc. If you are using something that starts up for every request, then you have to be aware of those kinds of things and design around them.