[nurbl]

I have hundreds of open tabs in FF most of the time and rarely close them. I use it a bit like emacs; ignore the "tab bar" and use ctrl-tab (with browser.ctrlTab.sortByRecentlyUsed set to true) or tab search (with %) to jump between them. The only reason I need to clean up my tabs now and then is the RAM usage.

[wintermutestwin]

>The only reason I need to clean up my tabs now and then is the RAM usage.

Total Suspender extension is critical if you have lots of tabs open at once.

[lost_tourist]

Not really true any longer, almost all modern browsers will background (unload) tabs when you get more than N windows (or memory % consumption). I think you have to turn that behavior off if you don't want it via about:config chrome://flags