[fragmede]

While everyone should be keenly aware the limitations of taking experimental results in mice and extrapolating to humans (aka, they often don't), doesn't that mean what we really have, is a bunch of well tested medication for meth addicts? Which; if there was a way to get meth addicts off meth, would be a boon?

[edgyquant]

Not necessarily addicts. You don’t have to be addicted to achieve psychosis you just need to take a certain amount. For me this amount is pretty small, I was prescribed adderal for awhile and even 20mg was enough to induce serious paranoia and the occasional hallucination

[freeone3000]

This wasn’t tested and wasn’t purported to test countering either addiction or acute overdose. This is a study showing the method of action. In mice (and humans, D2 receptor agonists are not new drugs), we have a method of countering the psychosis effect of meth. This has some value in ER and rehab settings where it is currently for healthcare provider safety; there is no evidence that it does anything else.

[monknomo]

It's not for addiction, but yes, if someone takes enough meth to induce psychosis, antipsychotics will reduce the psychosis.

[chrsig]

To be fair, there is a meth problem in the US.

Also there's a huge chasm between lab grade amphetamine and street meth.