[rgoulter]

More ergonomic peripherals are a good suggestion:

A good trackball instead of a mouse. (I love my Elecom Huge).

Non-standard keyboards where you can uses your thumbs (e.g. ZSA's moonlander) are a significant improvement over keyboards which retain an impractically large spacebar.

[cassianoleal]

Word of warning if you have smaller-than-average hands.

ZSA Moonlander is really not great or even very ergonomic for us. If you tent the keyboard, the thumb cluster has to be tilted down. In this case, the thumb keys are very hard to reach. If you put the cluster up, this improves only slightly, and now you can't tent the keyboard.

I stuck with mine for a few weeks but eventually gave up.