[colmmacc]

There's a number of UDP protocols that have large enough payloads to fragment. DNSSEC and EDNS0 in particular made it much more common, though the EDNS0 flag day in 2020 partially undid some of the damage by getting folks to ratchet down their EDNS0 buffer sizes.

1500 is absolutely not a pervasively usable WAN MTU, you're going to need pMTUd if you're sending 1500 byte packets broadly. Plenty of WAN links won't tolerate it. If you don't want to deal with fragmentation at all ... 500 is the minimum guaranteed MTU, but in practice it's exceptionally rare to see anything below about 1200 require fragmentation. But you can always only control what you send, not what others are sending you.