[mydriasis]

Largely depends on the existing culture of the company imo. I imagine in some climates it might come off as tone-deaf or degrading, whereas in others it might feel unifying or endearing.

From an outsider looking in on this one... I dunno. Firing your beloved hackeronies kind of grates.

[organsnyder]

Even the most non-objectionable term is going to sound tone-deaf in the context of layoffs. Just use the word "colleague" and keep it professional.