I spoke with the founder/owner of campusmemes.com asking the same questions. He basically said, "We operate business as usual until we get a C&D. Remove the image. Life goes on."
Hmm, The Monetization of Copyrighted Content without any Licenses sounds more like a service than a software product. Maybe try to obtain license agreements from the copyright holders and put the funding for agree'ed to licenses in the Kickstarter campaign.