There is no way you are serious, it's just a piece of paper. You can't compare it to one of the most famous websites.
It can pretty easily go both ways. The Mona Lisa have been a cultural icon for a long time, but Twitter has had a massive influence on culture since it's inception.
There are other similarities with Elon’s Twitter too. It’s hard to tell where the Mona Lisa is looking or what’s going on with her. There is a strange fog in the background and some scorched earth.
Seeing as Art is riddled with subjectivity, you absolutely could. And calling twitter “just a website” is disingenuous as it facilitates real-time global communication and a scale not previously reached by humans. I personally never used twitter, but I still respect what they built.
It can pretty easily go both ways. The Mona Lisa have been a cultural icon for a long time, but Twitter has had a massive influence on culture since it's inception.