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As a web programmer I understand where you're coming from, but as a UX designer I whole heartedly disagree.

Bootstrap is a wonderful tool for getting your app out there without having to do much on a design level. But I believe that websites with a distinct look and easy UI that reflects their functionality is way better than a monotonous string of websites with no distinction between their design.

For instance Twitter's design is beautifully streamlined for it's functionality, which is to show a constant flow of micro-information. As opposed to HN's listed threads which show link based data. These designs even though they differ seem "natural" based on their functionality and require little to no mental effort.

Good UX does not require mental effort.

Furthermore, a unique look is how others identify sites. It's Twitter's UI looked exactly like Facebook's, more would have trouble distinguishing the two. This would hurt the site's capability to make an impression in the user's memory.

With no distinction between websites, how will the casual user remember you?