[acuozzo]

Not OP, but I write in C for embedded platforms.

I use Vim and I write my build scripts in Python. Of the half-dozen dependencies I'm working with at the moment, half use GNU Autotools and the other half use CMake.

I know my targets and their respective toolchains in advance, so the automatic feature & quirks discovery of e.g. autoconf doesn't help all that much for the code I write myself. Plus, the targets I work with nowadays all have a compiler that's C11 and GCC-compatible to some degree, so my approach is generally to target ANSI C89/ISO C90 to the greatest extent possible; pulling in C99, C11, and GNU extensions only when necessary. I find myself reaching for <stdatomic.h> more and more nowadays, FWIW.