JS has a JIT compiler, so for long running programs it can very well execute native machine code in the exact same way as C (plus a GC occasionally meddling with things). Also, it’s not even a bad JIT compiler, huge amount of development went into making it good.
Standard Python is interpreted all the time, going from instruction to instruction giving a layer of abstraction that never disappears.
Standard Python is interpreted all the time, going from instruction to instruction giving a layer of abstraction that never disappears.