[ramraj07]

If you're comparing apples to apples similar size funds it still does matter - sure a16z is 300 partners but they share a culture and mission that evolves constantly and this will have a meaningful effect on your interaction with them.

[slap_shot]

That sounds nice in theory, but in reality, whether you raise from a firm of three partners or 300, you're going to work very closely with a single partner, and his or her competencies/style is mostly what your interaction with the "firm" is going to be. And you rarely, if ever, get to chose the partner with whom you work.